A comparison of effects on healing and recurrence from Atopic dermatitis Borage tea vs. corton

Background: Atopic dermatitis is a hereditary, chronic and recurrent disease (in 5%-10% of children).Topical corton is prescribed for this lesion as a routine cure. Studies show that patients with atopic dermatitis suffer from Essential fatty acids (EFA) deficiency. Borage tea is one of the sources enriched of EFA, it is a self – growing plant which is found abundantly in Iran. This clinical trial study was carried out in order to compare the effect of topical corton and Borage tea on healing and recurrence of atopic dermatitis on infants patient referred to dermatology clinics of Khorramabad city in spring and summer 2003. Materials and methods: This research is clinical experiment that two groups of 25 patients with atopic dermatitis between age 0-12 were selected randomly. After clinical examination and interview, the data recorded in a questionnaire, and then, corton and Borage juice prescribed for the patients in the form of every other one using blind method (7 days TDS). The cases were examined after 10 days. Both groups were examined for the third time twenty days after the beginning of treatment (10 days after cutting application of the medicine and borage tea) and then amount of healing, effectiveness and recurrent of disease were studied. Results: The rate of lesions healing, in response to application of topical Borage tea 27% was well, 4% moderate and 24% was poor, but in response to topical corton, it 24% was well,12% moderate and 64% was poor. Statistical X2 test with score 11.5 and (pv<0.003) showed difference significant between these 2 groups. Also, the lesions recurred in no body 10 days after discontinuation of borage tea application, while after using topical corton, disease recurrence rate was 64% moderate and 36% poor Exact fissure test (pv<0.001) showed difference significant between the two groups from view point of lesion recurrence. Conclusion: With respect to more healing and lesions recurrence due to Borage tea application, we suggest more studies about changing treatment methods of Atopic dermatitis, such as use of Borage.